![]() The result puts not only WeChat users at risk, but also anyone they communicate with. ![]() WeChat users “uniquely vulnerable to the very harm that the government claims that it is trying to prevent: the unauthorized access of WeChat users’ personal information.” It also completely flies in the face of decades of efforts to educate users about the importance of updates to improving Internet security, and encourages them to engage in risky behavior like downloading WeChat from untrusted third-party sources. users from using WeChat, the Commerce Department ordered American app stores, such as Apple’s and Google’s, not to host the application or to offer security updates to existing users. Our brief in support of the users on appeal focuses on the disastrous consequences of the ban for the Internet as a whole. In September, a federal magistrate judge in the Northern District of California issued a preliminary injunction, finding that the plaintiffs had raised serious questions about the constitutionality of the government’s ban on WeChat, and the government appealed to the Ninth Circuit Court of Appeals. So the Trump administration’s decision to ban WeChat has disastrous consequences for the ability of millions of Americans to communicate, in clear violation of their First Amendment rights.īefore the WeChat ban went into effect, a newly formed U.S.-based WeChat Users’ Alliance sued the Trump Administration-and succeeded in stopping the ban from going into effect. ![]() Due to WeChat’s reach and design, it has no equivalent, since many messaging applications developed in North America and Europe are banned or otherwise difficult to access within China. Many U.S.-based users of WeChat are members of the Chinese diaspora, and they use the application to stay in touch with friends, relatives, and contacts around the world, including in China. readers for its “ contagious vibe,” WeChat arguably enables even more important connections: it is a messaging application used by over a billion people worldwide, including 19 million users in the United States. ![]() jurisdiction.ĭespite the government’s claimed national security rationale, it was clear that the goal of these orders was censorship: entirely closing this country off from two wildly popular apps that provide the means of communication for millions of people. users “continues to threaten the national security, foreign policy, and economy of the United States,” and they directed the Commerce Department to draw up regulations to prohibit “any transaction” connected to either app within U.S. The executive orders claimed the spread of applications developed in China to U.S. government claims to deplore.Įarlier this year, President Trump issued a pair of executive orders intended to ban two massively popular Chinese-owned applications, TikTok and WeChat, from the United States. shores, we explain, the administration has taken an extraordinary step that weakens user security, intentionally dismembers infrastructure that keeps the Internet running, and emulates the very authoritarian tactics the U.S. In its rush to eradicate WeChat from U.S. Today, EFF-along with the Center for Democracy & Technology and the Internet Society-filed an amicus brief in support of U.S.-based users of the Chinese app WeChat, as they fight President Trump’s unconstitutional ban of the application.
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![]() Preference was given to articles of formal as well as commercial organizations trusted by ophthalmologists and those believed to be regularly accessed by patients such as Wikipedia. The keywords “eye gene therapy” or “voretigene neparvovec” or “Luxturna” were entered in and in major medical websites such as the American Academy of Ophthalmology (AAO) website, and relevant articles were selected for analysis from the top search results with exclusion of similar results from the same organization. As such, the goal of this study is to assess the accuracy, quality, and readability of online information regarding ocular applications of this gene therapy. 11 For these reasons, it is critical that the information patients obtain is accurate, complete, and easy to understand. 10 Low health literacy has been associated with poor medication adherence and adverse outcomes such as uncontrolled chronic disease and increased hospitalizations. Most patients read at an eighth grade level however, most sources of medical information are written at a tenth grade level or higher. 9 The content patients encounter would ideally be easy to comprehend. 8 The content acquired online influences patients’ health decisions. 8 Previous research shows about 62% of Internet users search the internet for health information. ![]() Millions of Americans search health-related information and seek medical advice online every day. With the approval of voretigene and the subsequent press coverage, patients with eye conditions are likely to learn about treatment options on the internet. 5 In the pivotal study, patients with this inherited retinal dystrophy were treated with subretinal injections of voretigene neparvovec and showed improvement in their functional vision which persisted for at least 4 years. 5 Voretigene neparvovec was unanimously approved by the FDA for patients with the biallelic RPE65 gene mutation form of hereditary retinal dystrophy. 4 In 2017, voretigene neparvovec (Luxturna, Spark Therapeutics, Philadelphia, PA, USA) became the third gene therapy to be approved by the Food and Drug Administration (FDA). It has been studied in years of experimentation to determine its use to treat several ocular conditions including neovascularization, retinitis pigmentosa, Stargardt disease, retinoblastoma, and more. Gene therapy has been of particular interest in ophthalmology. 2 Several trials have been conducted or are ongoing to evaluate the efficacy and safety of gene therapy, including but not limited to hematopoietic stem cell based gene therapy for β-thalassemia major, liver-directed gene therapy for hemophilia B, and T-cell immunotherapy for acute lymphoblastic leukemia. 1 Gene therapy was introduced in human subjects in the early 1990s, and currently, it is being recognized as a promising treatment option for multiple diseases. Gene augmentation therapy is a technique in which genetic material is introduced into a patient’s cells to treat or prevent disease. ![]() Spy Plane does a similar job to Intel but is an overall improvement in that it shares the information with the rest of your team, and theoretically lasts longer. Most COD players will tell you that there's nothing more powerful than the ability to see more and further on the minimap, so it's worth dedicating at least one Killstreak slot per match to either Intel or Spy Plane. That being said, we highly recommend that you don't overlook Intel just because it's the first Killstreak you unlock. When considering the 16 main Killstreaks, your own playstyle and skills should be a major factor in informing your decision, and no recommendation we give here should override your personal preferences. But it's also quite the feat to obtain one, so don't build your whole battle plan around bringing one. The V2 Rocket is rather obviously the best Killstreak in Vanguard, since it's literally an auto-win. V2 Rocket (25 Kills with guns): Call in a V2 Rocket that destroys the map and ends the game.īest Killstreaks in Call Of Duty: Vanguard.Local Informants (12 Kills): While active, reveals the location and direction of all enemies on the map.Firebombing Run (10 Kills): You mark a location for air support to rain fire from above in a massive line that kills enemies on impact and leaves behind a fiery wake that cannot be crossed by hostiles until it disperses.Attack Dogs (10 Kills): Deploy a pack of ferocious Attack Dogs that hunt down nearby enemies. ![]() Flamenaut (9 Kills): Equip a protective suit and Flamethrower with unlimited fuel.Emergency Airdrop (8 Kills): Drops three Care Packages, each rewarding a random Killstreak on pickup.Persists through death until ammo is depleted. Death Machine (7 Kills): Equips a Machine Gun (of a distinct type separate from the game's regular SMGs and LMGs) with explosive rounds and a fixed number of bullets.Bombing Run (7 Kills): Allied bombers make three passes, bombarding areas with high concentrations of enemies.Strafing Run (6 Kills): Calls in air support to strafe across a marked target area.The dog can be commanded to either guard a position or heel. Guard Dog (6 Kills): Calls in a Guard Dog for protection.Not lost upon player death but persists until ammo is depleted. War Machine (5 Kills): Equips a semi-automatic Grenade Launcher with a fixed number of grenades. ![]() Mortar Barrage (5 Kills): Toss a flare canister to mark an area for repeated mortar fire.Glide Bomb (5 Kills): A remote-controlled bomb with a large kill radius.Spy Plane (4 Kills): Calls in a Spy Plane that reveals enemy positions on the minimap to you and your allies.Counter Spy Plane (4 Kills): Calls in a Counter Spy Plane that obscures the minimap for all enemies.Care Package (4 Kills): Drops a single Care Package that rewards a random Killstreak on pickup.Intel (3 Kills): Reveals nearby enemies through repeated pings on the minimap over a short period.Read on below for details of every Killstreak in Vanguard, how many kills you need to unlock each one, and what they all do. There are 16 regular Killstreaks in Vanguard, as well as a coveted 17th that is really too powerful to be wielded by mortal hands and can only be obtained through a particularly impressive gameplay feat. List of Killstreaks in Call Of Duty: Vanguard ![]() Vanguard continues the series' tradition with its own selection of Killstreaks, a desirable set of perks that reward your prowess by giving you an even bigger advantage over the competition.īelow we've put together a list of every Killstreak in Vanguard and how to unlock them, as well as our selection of the best Killstreaks in Vanguard, and a quick explainer on how to equip and deploy them. What are the Killstreaks in Call Of Duty: Vanguard? As the name implies, Killstreaks are awarded in Call Of Duty multiplayer matches based on the number of kills you can rack up before dying yourself. ![]() ![]() The first transcontinental rail passengers arrived at the Pacific Railroad's original western terminus at the Alameda Terminal on September 6, 1869, where they transferred to the steamer Alameda for transport across the Bay to San Francisco. It brought the western states and territories into alignment with the northern Union states and made transporting passengers and goods coast-to-coast considerably quicker, safer and less expensive. The resulting coast-to-coast railroad connection revolutionized the settlement and economy of the American West. In the following six months, the last leg from Sacramento to San Francisco Bay was completed. The railroad opened for through traffic between Sacramento and Omaha on May 10, 1869, when CPRR President Leland Stanford ceremonially tapped the gold "Last Spike" (later often referred to as the " Golden Spike") with a silver hammer at Promontory Summit. The Union Pacific Railroad (UPRR) built 1,085 miles (1,746 km) from the road's eastern terminus at the Missouri River settlements of Council Bluffs and Omaha, Nebraska, westward to Promontory Summit. The Central Pacific Railroad Company of California (CPRR) constructed 690 miles (1,110 km) east from Sacramento to Promontory Summit, Utah Territory. The Western Pacific Railroad Company built 132 miles (212 km) of track from the road's western terminus at Alameda/ Oakland to Sacramento, California. Building was financed by both state and US government subsidy bonds as well as by company-issued mortgage bonds. The rail line was built by three private companies over public lands provided by extensive US land grants. ![]() rail network at Council Bluffs, Iowa, with the Pacific coast at the Oakland Long Wharf on San Francisco Bay. 1863–1869: Union Pacific built west (blue line), Central Pacific built east (red line) and Western Pacific built the last leg (green line) to complete the railroadĪmerica's first transcontinental railroad (known originally as the " Pacific Railroad" and later as the " Overland Route") was a 1,911-mile (3,075 km) continuous railroad line constructed between 18 that connected the existing eastern U.S. Now it all boils down to which of the two compression utilities is better- Winzip, who has been around since forever, or 7-zip, the free, open-source newcomer? Winzip also uses less memory as compared to 7-zip, which is really handy when you're using a slower device, laptop or desktop computer. ![]() This is probably because Winzip has an algorithm that produces better compression quality and speed. In zipping and unzipping tests, Winzip came out as the clear winner. Winzip standard costs $29.95, and the Pro version costs $59.95. 7-zip can work indefinitely as long as you keep it on your computer, while Winzip has a trial period of 21 days before reminding you to pay. You can bet that any zip file can be opened on virtually any system platform, including the Mac, iOS and Android without having to download an app.īoth software have free versions, but that's where the similarity ends. Winzip has been around since time immemorial, which gives it the definite edge in compatibility. Though there's a small size difference after compressing the same file, 7-Zip edges out WinZip. Integration with Windows is readily available, and it doubles as a capable file manager. Unpacking is doable for these file types as well- fat, ext, xar, iso and many others.Īs for security, the app boasts strong AES-256 encryption quality for their native 7z format. The software supports the unpacking and packing of popular formats such as zip, tar, gzip, xz and 7z. 7z with a promise of better compression and smaller files. What's more, it brought its own file extension, the. HTML links can be shared for faster access.ħ-Zip quickly gained prominence in the file compression world as a free and speedy file archiver. Winzip has evolved with the times, and now has a 'share anywhere' feature that allows users to send large files via instant messaging, social media, to the cloud or email. There's also the addition of watermarks, which deter unauthorized copying. All zipped files are encrypted to keep data and information from prying eyes. Security is a major concern nowadays, and with Winzip you won't have to worry. Plus, you get a file management platform that allows you to edit, open, move, find and share your files, whether they're located in a network, a computer or the cloud. The latest version of Winzip is Winzip 23, which only goes to show you how far the software has gone.īy itself, Winzip can unzip all major formats, including zip, rar, tar, zipx and more. The granddaddy of all zip utilities, Winzip has been around since the time of Windows 95, 98 and so on. Let's take a look at the main features, pros, and cons, and other things that can give you a more informed decision in the end. Both Winzip download and 7-Zip download are small and fast enough that you can get them installed in less than a minute or two. ![]() A quick search for 'compression tools for Windows' will give you Winzip and 7zip, but which one of them is better? More importantly, which software will be the right fit for what you need?īoth software has their own main websites and list of features. impressionist, oil on canvas, in the style of Claude Monet ::3 This an evocative representation of technology as the new faith of humanity, by showing people praying at the altar of technology to a techno Christ, in a traditional impressioniti style. ::3 Dark ambience, light rays shine from the tall stained glass windows, volume lighting, dramatic lighting, cinematic lighting. 1pc Calming Green Forest Canvas Wall Art - Waterfall Landscape Painting for Living Room, Bedroom, Office - Nature Scene Canvas Print Artwork for Home Decor - No Frame Required 2.98. ![]() ![]() Inside a huge futuristic techno cathedral ::4 The mood is futuristic, ceremonial, grandiose. Name: Pnf Set Of 3 landscape scenery of vastu waterfall Painting Material: Synthetic Type: Painting Print or Pattern Type: Nature Frame Type: Framed Product. The crowd stands in adoration of Him, hands risen. Enjoy to watch my easy waterfall landscape painting tutorial for beginners.Follow me creating this beautiful Waterfall landscape painting step by step.See ho. ![]() Out-of-this-world impressionist oil painting of an awe inspiring cyber Christ hanging from a techno cross ::5 The Jesus on the cross has intricate futuristic cybernetic implants, and faces a congregation exulting believers, who worship him. 5 out of 5 stars Sale Price 58.50 Original Price 65. If it's the latter, you can try resetting his body clock by getting him used to being awake during the day and sleeping at night. Your cat might be meowing for attention, but he might also be meowing because he's got his days and nights completely flipped. Take a look at these other tips you can try to keep your pet from waking you in the early morning hours: Reset your cat’s body clock. If your cat does experience mental health issues, your veterinarian may prescribe anti-anxiety medication as well as change the environment in order to keep your cat calm. ![]() Your vet will take a look at your cat and rule out any physical causes before concluding that it's psychological. ![]() If your cat is crying during the night and you can't figure out the cause, consult your veterinarian for help. ![]() It could be that your cat feels like he needs more love and attention at night. These cats often make noise to get attention from their owners. When you leave for work or when other people come over, it may make them feel alone and abandoned. Cats can be a bit more social than many pet owners realize. Does your cat need to be neutered? Make the vet appointment today.Ĭonsider another possibility: Your feline might be lonely.Could she have dementia? Here again, the vet can help.Might the cat bed be uncomfortable or the litter tray in need of cleaning? These are easy to solve, too.Is she bored? Try investing in a puzzle toy, a cat tree, or a scratcher.If your cat is super active at night, consider what the animal could be telling you: How do I teach my cat to stay quiet at night? In this case, spaying or neutering your pet is a great solution - for more reasons than just stopping the meowing. Cats reach sexual maturity at around four months of age, so even a fairly young kitten may be seeking her Romeo or his Juliet at 2:30 in the morning when you're asleep. On the younger end of things, a female cat in heat or a tom (an intact male cat) may yowl at night because they are looking for a partner. In this case, the cat may be confused or feel insecure at nighttime when the household is in bed. Could your cat be feeling under the weather? Hypertension, hyperthyroidism, and cystitis can all cause cats to meow due to distress or pain, and senior cats sometimes experience cognitive decline, similar to dementia in people. If you're sure your cat is getting enough attention and exercise, though, consider other reasons for meowing.Ĭat behavior is often a sign of cat health. Get that cat some toys! Then be sure to play with her for 20-60 minutes a day. Those reasons can cause cat owners to worry and with good reason!Īfter all, excessive meowing due to boredom is pretty easy to solve. Those are all fairly benign reasons for nighttime meowing, but occasionally, cats meow because they're distressed, disabled, demented, or looking for love. More often than not, they're meowing just because they're lonely and want to play - even when their people are fast asleep. At other times, your cat may need you to replenish their food or water. If you've ruled out health issues, though, consider some of these tactics to stop your cat from meowing all night: Why does your cat meow at night?Ĭats meow at night for all kinds of reasons. Like the rest of us, cats can have excessive vocalization because of illness or pain. Once you figure out why your cat fusses at night, you'll find it easier to calm him.īefore trying any of our 6 tips, be sure to take your cat to the vet. Many cat lovers are dragging out of bed to quiet a feisty feline.Ī cat’s night-time vocalizations are his way of signaling a need such as hunger, thirst, or loneliness. ![]() Is your cat’s meowing keeping you up at night? You're not alone. |
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